CORRELATION BETWEEN POSITIVE AND NEGATIVE SYNDROME SCALE (PANSS) SCORES AND HOMOCYSTEINE LEVELS IN MEN WITH SCHIZOPHRENIA BATAKNESE TRIBE AT PSYCHIATRIC HOSPITAL OF PROF. M. ILDREM MEDAN

Authors

  • Ridha Rizki , Elmeida Effendy , Vita Camellia , Freddy Subastian

Abstract

In people with schizophrenia, high serum homocysteine levels are associated with poor clinical
symptoms, especially in the negative symptom domain and general psychopathology with
PANSS score assessment. Many studies have been studied about consensus that homocysteine is
an important indicator for mental disorders such as autism, schizophrenia, depression, and
bipolar disorder. To find out the correlation between PANSS scores and homocysteine levels in
men with schizophrenia in the Batak tribe in the mental hospital prof. M. Ildrem Medan. A
correlation analytic study with cross sectional design using PANSS score measurement and
examination of serum homocysteine levels in men with schizophrenia of the Batak tribe during
the July-September 2019 period in the inpatient installation of psychiatric hospital of Prof.
Ildrem Medan. A total of 105 subjects who met the inclusion criteria of men with schizophrenia
of the Batak tribe who were diagnosed with PPDGJ III, ages 20-45 years, length of illness ≥ 2
years. Participants who suffergeneral medical disorders and or other comorbidities, the use of
other psychoactive substances and use of supplements that contain folic acid and vitamin B
exclusion from this study. There is a significant correlation between positive PANSS scores and
Homocysteine levels in Batak schizophrenic men, a correlation coefficient of r = 0.529 shows a
positive correlation with moderate correlation strength (r = 0.4 - <0.6)) with a value of p = 0.001). There is a correlation between negative PANSS scores and Homocysteine levels in the
Batak schizophrenic men, the correlation coefficient is r = 0.544 with moderate correlation
strength (r = 0.4 - <0.6) with p = 0.001. There is a significant correlation between PANSS scores
of general psychopalogy and Homocysteine levels in schizophrenic men of the Batak tribe, the
correlation coefficient of r = 0.633 with the strength of strong correlations (r = 0.6 - <0.8) with p
= 0.001. There is a significant correlation between the PANSS Total Score and Homocysteine
Levels in men with schizophrenia of the Batak tribe, the correlation coefficient of r = 0.668
shows a positive correlation with strong strength (r = 0.6 - <0.8) with a value of p = .001.

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Published

2020-11-28

How to Cite

Ridha Rizki , Elmeida Effendy , Vita Camellia , Freddy Subastian. (2020). CORRELATION BETWEEN POSITIVE AND NEGATIVE SYNDROME SCALE (PANSS) SCORES AND HOMOCYSTEINE LEVELS IN MEN WITH SCHIZOPHRENIA BATAKNESE TRIBE AT PSYCHIATRIC HOSPITAL OF PROF. M. ILDREM MEDAN. PalArch’s Journal of Archaeology of Egypt / Egyptology, 17(6), 1505 - 1518. Retrieved from http://mail.palarch.nl/index.php/jae/article/view/1008