ESTIMATION OF SERUM LIPID PROFILE IN CHOLELITHIASIS PATIENTS

Abstract

Gallstones happen to be the most prevalent among varied pathologies affecting the biliary system. Gall bladder takes precedence over all other sites in the biliary system in formation of stone, owing to its physiological function of concentration of bile. There has been a significant increase in incidence of cholelithiasis in the world including India. The prevalence of gallstones is increasing due to the changes in dietary pattern. A fat, fertile, flatulent, female, fifty is the classical sufferer from symptomatic gallstones. The present study was conducted to estimate the serum cholesterol and Triglycerides levels in the gallstone patients. 50 healthy clinically normal subjects of age group between 20 – 60 yrs are selected as controls.50 patients of age group 20-60 yrs from gastroenterology department who have been diagnosed as having cholelithiasis by imaging namely ultrasound abdomen, CT abdomen, MRCP are selected as study group. Serum lipid profile was estimated using standard methods. HDL levels were decreased in cholelithiasis patients whereas Total cholesterol, LDL levels, triglycerides were elevated but were not significant. The study concluded that there was a significant decrease in HDL levels and significant increase in triglycerides levels in cholelithiasis patients when compared to the control group.